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GSK Reports the EMA’s Acceptance of Nucala (Mepolizumab) as an Add-on Treatment for COPD

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GSK

GSK Reports the EMA’s Acceptance of Nucala (Mepolizumab) as an Add-on Treatment for COPD

Shots:

  • The EMA has accepted label expansion application of Nucala as an add-on maintenance treatment of COPD pts with an eosinophilic phenotype based on P-III (MATINEE) study
  • The MATINEE study assessing Nucala (100mg, Q4W, SC) vs PBO in addition to inhaled triple therapy in COPD pts (n=804) with type 2 inflammation achieved its 1EP, showing significantly reduced mod. or sev. exacerbations over 52-104wks. Data to be highlighted at future conferences
  • Nucala (mepolizumab) is a mAb that inhibits IL-5 to reduce blood eosinophil level for producing anti-inflammatory activity in eosinophilic asthma, EGPA & CRSwNP

Ref: GSK  | Image: GSK 

Related News:- GSK Presents Pooled Analysis from P-III (ANCHOR-1 & 2) Trial of Depemokimab for CRSwNP at AAAAI/WAO Joint Congress 2025

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Ridhi Rastogi

Ridhi is an avid secondary researcher who follows trends in the biopharmaceutical and healthcare sectors to curate engaging content for the global audience. She works as a news editor at PharmaShots and loves to read books and explore new destinations.

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