
GSK Reports the EMA’s Acceptance of Nucala (Mepolizumab) as an Add-on Treatment for COPD
Shots:
- The EMA has accepted label expansion application of Nucala as an add-on maintenance treatment of COPD pts with an eosinophilic phenotype based on P-III (MATINEE) study
- The MATINEE study assessing Nucala (100mg, Q4W, SC) vs PBO in addition to inhaled triple therapy in COPD pts (n=804) with type 2 inflammation achieved its 1EP, showing significantly reduced mod. or sev. exacerbations over 52-104wks. Data to be highlighted at future conferences
- Nucala (mepolizumab) is a mAb that inhibits IL-5 to reduce blood eosinophil level for producing anti-inflammatory activity in eosinophilic asthma, EGPA & CRSwNP
Ref: GSK | Image: GSK
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